TrialWatch
Byetta weight loss trial
Weight management is a key ingredient in fighting or controlling diabetes. This trial seeks to find out the effects of Byetta (exenatide), an injectable drug that reduces the level of blood glucose, on weight loss in people with type 2 diabetes. Researchers are looking for 190 people with type 2 diabetes to participate in this 24-week trial. To be eligible, you must be between 18 and 75 years old and have been treated with a stable dose of metformin, sulfonylurea, or a combination of the two, for at least six weeks prior to screening. Enrollment is in nine U.S. states including Florida, Massachusetts, and Minnesota. Please contact the Eli Lilly Clinical Trials Support Center at 1-877-285-4559 for more information.
Lantus insulin "All to Target" Trial
Here is a big trial on insulin coming your way. If you have type 2 diabetes and are having difficulty managing your diabetes with oral therapy, this year-long trial may be of special interest to you. In this study, researchers will look into the effects that the administration of a once-daily insulin substitute, Lantus insulin, has in patients with type 2 diabetes, in contrast to a twice-daily regimen of premixed insulin containing a 70/30 mixture of long-acting and fast-acting insulin respectively. Long-acting insulin remains active in the blood for over 24 hours, while fast-acting insulin has its maximum effect 45-90 minutes after being administered. The trial conclusions will be based upon the proportion of participants achieving a target A1C level in the group using Lantus insulin compared with the group on premixed insulin. Researchers are currently recruiting participants for the New Jersey-based trial. To be eligible, you must be between 30 and 80 years old and have an A1C greater than 7.5%. To find out more information, you can contact Public Registry USMA at PublicRegistryUSMA@sanofi-aventis.com.
Coping with type 1 diabetes
This study aims to determine how one's ability to cope with diabetes affects blood glucose control in type 1s between the ages of 8 years and 20 years. The trial is taking place at the Baylor College of Medicine, Texas Children’s Hospital in Houston. Researchers are seeking 300 type 1 diabetes patients to learn about how dealing with the hourly responsibilities of blood glucose monitoring, insulin dosing, diet, and exercise affects A1c levels. Please contact Dr. Krishna Hassan (krishnah@bcm.tmc.edu) at 832-822-3785 or Dr. Rubina A Heptulla (raheptul@texaschildrenshospital.org) at 832-822-3779 for more details.